GLP-1 (Glucagon-like peptide-1)
A hormone that plays a key role in regulating blood sugar levels and appetite by stimulating insulin release and slowing gastric emptying.
GLP-1 is a naturally occurring hormone produced in the gut in response to eating. It binds to GLP-1 receptors in the pancreas, stimulating the release of insulin when blood sugar levels are high.
In addition to its role in glucose metabolism, GLP-1 acts on the brain to promote a feeling of fullness (satiety) and slows the rate at which the stomach empties. This dual action makes synthetic GLP-1 receptor agonists highly effective for chronic weight management.
Examples of GLP-1 receptor agonists include semaglutide (Wegovy, Ozempic) and liraglutide (Saxenda).